Menin

Intramolecular

A redox-regulated disulphide may form within Menin between cysteines 230 and 241. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7o9x

Structure name

crystal structure of human menin with fragment 16

Structure deposition date

2021-04-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

A0A024R5E3

Residue number A

230

Residue number B

241

Peptide name

Menin

Ligandability

Cysteine 230 of Menin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.