ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Immunoglobulin lambda variable 1-36

Intramolecular
Cysteine 41 and cysteine 108
A redox-regulated disulphide may form within Immunoglobulin lambda variable 1-36 between cysteines 41 and 108 (22 and 89 respectively in this structure).

Details

Redox score ?
70
PDB code
6mid
Structure name
cryo-em structure of the zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195
Structure deposition date
2018-09-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
92
Minimum pKa ?
8
% buried
85
Peptide accession
A0A0B4J1U3
Residue number A
41
Residue number B
108
Peptide name
Immunoglobulin lambda variable 1-36

Ligandability

Cysteine 41 of Immunoglobulin lambda variable 1-36

Cysteine 108 of Immunoglobulin lambda variable 1-36

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