Protein kinase C delta type
Intermolecular
Cysteine 280 and cysteine 272
Cysteine 247 and cysteine 280
Cysteine 264 and cysteine 247
Cysteine 261 and cysteine 247
Cysteine 272 and cysteine 264
Intramolecular
Cysteine 247 and cysteine 272
Cysteine 244 and cysteine 247
Cysteine 261 and cysteine 264
Cysteine 261 and cysteine 280
Cysteine 264 and cysteine 280
Cysteine 244 and cysteine 272
7l92 G 280 J 272
A redox-regulated disulphide may form between two units of Protein kinase C delta type at cysteines 280 and 272. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
58
Peptide A name
Protein kinase C delta type
Peptide B name
Protein kinase C delta type
Peptide A accession
A0A140UHX0
Peptide B accession
A0A140UHX0
Peptide A residue number
280
Peptide B residue number
272
Ligandability
Cysteine 280 of Protein kinase C delta type
Cysteine 272 of Protein kinase C delta type
7l92 M 247 P 280
A redox-regulated disulphide may form between two units of Protein kinase C delta type at cysteines 247 and 280. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
70
Peptide A name
Protein kinase C delta type
Peptide B name
Protein kinase C delta type
Peptide A accession
A0A140UHX0
Peptide B accession
A0A140UHX0
Peptide A residue number
247
Peptide B residue number
280
Ligandability
Cysteine 247 of Protein kinase C delta type
Cysteine 280 of Protein kinase C delta type
7l92 G 264 J 247
A redox-regulated disulphide may form between two units of Protein kinase C delta type at cysteines 264 and 247. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
64
Minimum pKa ?
9
% buried
64
Peptide A name
Protein kinase C delta type
Peptide B name
Protein kinase C delta type
Peptide A accession
A0A140UHX0
Peptide B accession
A0A140UHX0
Peptide A residue number
264
Peptide B residue number
247
Ligandability
Cysteine 264 of Protein kinase C delta type
Cysteine 247 of Protein kinase C delta type
7l92 G 261 J 247
A redox-regulated disulphide may form between two units of Protein kinase C delta type at cysteines 261 and 247. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
nan
Peptide A name
Protein kinase C delta type
Peptide B name
Protein kinase C delta type
Peptide A accession
A0A140UHX0
Peptide B accession
A0A140UHX0
Peptide A residue number
261
Peptide B residue number
247
Ligandability
Cysteine 261 of Protein kinase C delta type
Cysteine 247 of Protein kinase C delta type
7l92 M 272 P 264
A redox-regulated disulphide may form between two units of Protein kinase C delta type at cysteines 272 and 264. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
33
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
64
Minimum pKa ?
17
% buried
66
Peptide A name
Protein kinase C delta type
Peptide B name
Protein kinase C delta type
Peptide A accession
A0A140UHX0
Peptide B accession
A0A140UHX0
Peptide A residue number
272
Peptide B residue number
264
Ligandability
Cysteine 272 of Protein kinase C delta type
Cysteine 264 of Protein kinase C delta type
7lf3 A 247 A 272
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 247 and 272.
Details
Redox score ?
87
PDB code
7lf3
Structure name
c1b domain of protein kinase c in complex with diacylglycerol-lactone ajh-836
Structure deposition date
2021-01-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
5
% buried
0
Peptide accession
A0A140UHX0
Residue number A
247
Residue number B
272
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 247 of Protein kinase C delta type
Cysteine 272 of Protein kinase C delta type
7knd A 244 A 247
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 244 and 247.
Details
Redox score ?
87
PDB code
7knd
Structure name
c1b domain of protein kinase c in apo form
Structure deposition date
2020-11-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
5
% buried
8
Peptide accession
A0A140UHX0
Residue number A
244
Residue number B
247
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 244 of Protein kinase C delta type
Cysteine 247 of Protein kinase C delta type
7l92 J 261 J 264
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 261 and 264.
Details
Redox score ?
87
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
0
Peptide accession
A0A140UHX0
Residue number A
261
Residue number B
264
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 261 of Protein kinase C delta type
Cysteine 264 of Protein kinase C delta type
7l92 P 261 P 280
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 261 and 280.
Details
Redox score ?
79
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
nan
Peptide accession
A0A140UHX0
Residue number A
261
Residue number B
280
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 261 of Protein kinase C delta type
Cysteine 280 of Protein kinase C delta type
7l92 G 264 G 280
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 264 and 280.
Details
Redox score ?
78
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
49
Peptide accession
A0A140UHX0
Residue number A
264
Residue number B
280
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 264 of Protein kinase C delta type
Cysteine 280 of Protein kinase C delta type
7l92 J 244 J 272
A redox-regulated disulphide may form within Protein kinase C delta type between cysteines 244 and 272. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
60
PDB code
7l92
Structure name
c1b domain of protein kinase c in complex with diacylglycerol and dodecyl 2-(trimethylammonio)ethyl phosphate
Structure deposition date
2021-01-01
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
18
% buried
nan
Peptide accession
A0A140UHX0
Residue number A
244
Residue number B
272
Peptide name
Protein kinase C delta type
Ligandability
Cysteine 244 of Protein kinase C delta type
Cysteine 272 of Protein kinase C delta type
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