a tool for identifying drug-targetable redox-active disulphides

Anti-vesicular stomatitis virus N VHH

Intramolecular

Cysteine 22 and cysteine 96

A redox-regulated disulphide may form within Anti-vesicular stomatitis virus N VHH between cysteines 22 and 96.

Details

Redox score ?

81

PDB code

Structure name

vesicular stomatits virus n protein in complex with inhibitory nanobody 1307

Structure deposition date

2017-01-19

Thiol separation (Å)

2

Half-sphere exposure sum ?

81

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

22

Residue number B

96

Peptide name

Anti-vesicular stomatitis virus N VHH

Ligandability

Cysteine 22 of Anti-vesicular stomatitis virus N VHH

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 96 of Anti-vesicular stomatitis virus N VHH

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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