glycerol kinase
Intermolecular
Cysteine 354 and cysteine 354
Intramolecular
Cysteine 287 and cysteine 388
Cysteine 293 and cysteine 388
Cysteine 269 and cysteine 287
Cysteine 287 and cysteine 293
Cysteine 331 and cysteine 354
Cysteine 196 and cysteine 256
Cysteine 283 and cysteine 374
7nie A 354 B 880
A redox-regulated disulphide may form between two units of glycerol kinase at cysteines 354 and 354 (354 and 880 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
7
Half-sphere exposure sum ?
98
Minimum pKa ?
12
% buried
100
Peptide A name
glycerol kinase
Peptide B name
glycerol kinase
Peptide A accession
A0A287BD08
Peptide B accession
A0A287BD08
Peptide A residue number
354
Peptide B residue number
354
Ligandability
Cysteine 354 of glycerol kinase
Cysteine 354 of glycerol kinase
7nie A 287 A 388
A redox-regulated disulphide may form within glycerol kinase between cysteines 287 and 388.
Details
Redox score ?
65
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
6
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
20
Peptide accession
A0A287BD08
Residue number A
287
Residue number B
388
Peptide name
glycerol kinase
Ligandability
Cysteine 287 of glycerol kinase
Cysteine 388 of glycerol kinase
7nie O 293 O 388
A redox-regulated disulphide may form within glycerol kinase between cysteines 293 and 388. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
42
Peptide accession
A0A287BD08
Residue number A
293
Residue number B
388
Peptide name
glycerol kinase
Ligandability
Cysteine 293 of glycerol kinase
Cysteine 388 of glycerol kinase
7nie A 269 A 287
A redox-regulated disulphide may form within glycerol kinase between cysteines 269 and 287. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
61
Peptide accession
A0A287BD08
Residue number A
269
Residue number B
287
Peptide name
glycerol kinase
Ligandability
Cysteine 269 of glycerol kinase
Cysteine 287 of glycerol kinase
7nie A 287 A 293
A redox-regulated disulphide may form within glycerol kinase between cysteines 287 and 293. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
77
Minimum pKa ?
10
% buried
58
Peptide accession
A0A287BD08
Residue number A
287
Residue number B
293
Peptide name
glycerol kinase
Ligandability
Cysteine 287 of glycerol kinase
Cysteine 293 of glycerol kinase
7nie B 857 B 880
A redox-regulated disulphide may form within glycerol kinase between cysteines 331 and 354 (857 and 880 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
90
Minimum pKa ?
13
% buried
100
Peptide accession
A0A287BD08
Residue number A
331
Residue number B
354
Peptide name
glycerol kinase
Ligandability
Cysteine 331 of glycerol kinase
Cysteine 354 of glycerol kinase
7nie P 722 P 782
A redox-regulated disulphide may form within glycerol kinase between cysteines 196 and 256 (722 and 782 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
96
Minimum pKa ?
11
% buried
78
Peptide accession
A0A287BD08
Residue number A
196
Residue number B
256
Peptide name
glycerol kinase
Ligandability
Cysteine 196 of glycerol kinase
Cysteine 256 of glycerol kinase
7nie B 809 B 900
A redox-regulated disulphide may form within glycerol kinase between cysteines 283 and 374 (809 and 900 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
31
PDB code
7nie
Structure name
putative glycerol kinase-like proteins anchored on an array of voltage dependent anion channels in the outer mitochondrial membrane of pig sperm mitochondria
Structure deposition date
2021-02-12
Thiol separation (Å)
9
Half-sphere exposure sum ?
91
Minimum pKa ?
11
% buried
100
Peptide accession
A0A287BD08
Residue number A
283
Residue number B
374
Peptide name
glycerol kinase
Ligandability
Cysteine 283 of glycerol kinase
Cysteine 374 of glycerol kinase
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