ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Intermolecular
Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 151
A redox-regulated disulphide may form between cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 151 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (155 and 141 respectively in this structure).

Details

Redox score ?
71
PDB code
7vy1
Structure name
membrane arm of deactive state ci from q10 dataset
Structure deposition date
2021-11-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
8
% buried
99
Peptide A name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Peptide B name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Peptide A accession
A0A4X1VYV0
Peptide B accession
A0A287BMW6
Peptide A residue number
155
Peptide B residue number
151

Ligandability

Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 151 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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