PREX1
Intramolecular
Cysteine 879 and cysteine 968
Cysteine 879 and cysteine 1336
Cysteine 879 and cysteine 972
Cysteine 972 and cysteine 1336
Cysteine 963 and cysteine 1032
Cysteine 963 and cysteine 968
Cysteine 1021 and cysteine 1578
Cysteine 968 and cysteine 1328
Cysteine 879 and cysteine 1328
Cysteine 1021 and cysteine 1336
More...Cysteine 1380 and cysteine 1572
Cysteine 972 and cysteine 1021
Cysteine 968 and cysteine 972
6pcv A 879 A 968
A redox-regulated disulphide may form within PREX1 between cysteines 879 and 968. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
5
Half-sphere exposure sum ?
95
Minimum pKa ?
11
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
879
Residue number B
968
Peptide name
PREX1
Ligandability
Cysteine 879 of PREX1
Cysteine 968 of PREX1
6pcv A 879 A 1336
A redox-regulated disulphide may form within PREX1 between cysteines 879 and 1336. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
89
Minimum pKa ?
11
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
879
Residue number B
1336
Peptide name
PREX1
Ligandability
Cysteine 879 of PREX1
Cysteine 1336 of PREX1
6pcv A 879 A 972
A redox-regulated disulphide may form within PREX1 between cysteines 879 and 972. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
96
Minimum pKa ?
11
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
879
Residue number B
972
Peptide name
PREX1
Ligandability
Cysteine 879 of PREX1
Cysteine 972 of PREX1
6pcv A 972 A 1336
A redox-regulated disulphide may form within PREX1 between cysteines 972 and 1336. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
6
Half-sphere exposure sum ?
95
Minimum pKa ?
13
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
972
Residue number B
1336
Peptide name
PREX1
Ligandability
Cysteine 972 of PREX1
Cysteine 1336 of PREX1
6pcv A 963 A 1032
A redox-regulated disulphide may form within PREX1 between cysteines 963 and 1032. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
10
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
29
Peptide accession
A0A2X0SFH1
Residue number A
963
Residue number B
1032
Peptide name
PREX1
Ligandability
Cysteine 963 of PREX1
Cysteine 1032 of PREX1
6pcv A 963 A 968
A redox-regulated disulphide may form within PREX1 between cysteines 963 and 968. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
9
% buried
71
Peptide accession
A0A2X0SFH1
Residue number A
963
Residue number B
968
Peptide name
PREX1
Ligandability
Cysteine 963 of PREX1
Cysteine 968 of PREX1
6pcv A 1021 A 1578
A redox-regulated disulphide may form within PREX1 between cysteines 1021 and 1578. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
91
Minimum pKa ?
12
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
1021
Residue number B
1578
Peptide name
PREX1
Ligandability
Cysteine 1021 of PREX1
Cysteine 1578 of PREX1
6pcv A 968 A 1328
A redox-regulated disulphide may form within PREX1 between cysteines 968 and 1328. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
7
Half-sphere exposure sum ?
94
Minimum pKa ?
13
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
968
Residue number B
1328
Peptide name
PREX1
Ligandability
Cysteine 968 of PREX1
Cysteine 1328 of PREX1
6pcv A 879 A 1328
A redox-regulated disulphide may form within PREX1 between cysteines 879 and 1328. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
88
Minimum pKa ?
11
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
879
Residue number B
1328
Peptide name
PREX1
Ligandability
Cysteine 879 of PREX1
Cysteine 1328 of PREX1
6pcv A 1021 A 1336
A redox-regulated disulphide may form within PREX1 between cysteines 1021 and 1336. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
27
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
91
Minimum pKa ?
12
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
1021
Residue number B
1336
Peptide name
PREX1
Ligandability
Cysteine 1021 of PREX1
Cysteine 1336 of PREX1
6pcv A 1380 A 1572
A redox-regulated disulphide may form within PREX1 between cysteines 1380 and 1572. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
26
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
10
Half-sphere exposure sum ?
89
Minimum pKa ?
13
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
1380
Residue number B
1572
Peptide name
PREX1
Ligandability
Cysteine 1380 of PREX1
Cysteine 1572 of PREX1
6pcv A 972 A 1021
A redox-regulated disulphide may form within PREX1 between cysteines 972 and 1021. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
26
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
96
Minimum pKa ?
12
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
972
Residue number B
1021
Peptide name
PREX1
Ligandability
Cysteine 972 of PREX1
Cysteine 1021 of PREX1
6pcv A 968 A 972
A redox-regulated disulphide may form within PREX1 between cysteines 968 and 972. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
23
PDB code
6pcv
Structure name
single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Structure deposition date
2019-06-18
Thiol separation (Å)
10
Half-sphere exposure sum ?
101
Minimum pKa ?
13
% buried
100
Peptide accession
A0A2X0SFH1
Residue number A
968
Residue number B
972
Peptide name
PREX1
Ligandability
Cysteine 968 of PREX1
Cysteine 972 of PREX1
If this tool was useful for finding a disulphide, please cite: