RNA polymerase II subunit K
Intramolecular
Cysteine 22 and cysteine 36
Cysteine 22 and cysteine 39
Cysteine 19 and cysteine 22
Cysteine 19 and cysteine 36
Cysteine 19 and cysteine 39
Cysteine 36 and cysteine 39
7f4g L 22 L 36
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 22 and 36.
Details
Redox score ?
84
PDB code
7f4g
Structure name
structure of rpap2-bound rna polymerase ii
Structure deposition date
2021-06-18
Thiol separation (Å)
3
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
9
Peptide accession
A0A4X1TRS6
Residue number A
22
Residue number B
36
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 22 of RNA polymerase II subunit K
Cysteine 36 of RNA polymerase II subunit K
7f4g L 22 L 39
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 22 and 39.
Details
Redox score ?
82
PDB code
7f4g
Structure name
structure of rpap2-bound rna polymerase ii
Structure deposition date
2021-06-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
7
% buried
11
Peptide accession
A0A4X1TRS6
Residue number A
22
Residue number B
39
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 22 of RNA polymerase II subunit K
Cysteine 39 of RNA polymerase II subunit K
7f4g L 19 L 22
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 19 and 22.
Details
Redox score ?
81
PDB code
7f4g
Structure name
structure of rpap2-bound rna polymerase ii
Structure deposition date
2021-06-18
Thiol separation (Å)
3
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
22
Peptide accession
A0A4X1TRS6
Residue number A
19
Residue number B
22
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 19 of RNA polymerase II subunit K
Cysteine 22 of RNA polymerase II subunit K
7f4g L 19 L 36
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 19 and 36.
Details
Redox score ?
76
PDB code
7f4g
Structure name
structure of rpap2-bound rna polymerase ii
Structure deposition date
2021-06-18
Thiol separation (Å)
3
Half-sphere exposure sum ?
60
Minimum pKa ?
11
% buried
28
Peptide accession
A0A4X1TRS6
Residue number A
19
Residue number B
36
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 19 of RNA polymerase II subunit K
Cysteine 36 of RNA polymerase II subunit K
7f4g L 19 L 39
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 19 and 39.
Details
Redox score ?
73
PDB code
7f4g
Structure name
structure of rpap2-bound rna polymerase ii
Structure deposition date
2021-06-18
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
11
% buried
30
Peptide accession
A0A4X1TRS6
Residue number A
19
Residue number B
39
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 19 of RNA polymerase II subunit K
Cysteine 39 of RNA polymerase II subunit K
7ega z 36 z 39
A redox-regulated disulphide may form within RNA polymerase II subunit K between cysteines 36 and 39.
Details
Redox score ?
72
PDB code
7ega
Structure name
tfiid-based intermediate pic on puma promoter
Structure deposition date
2021-03-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
47
Minimum pKa ?
10
% buried
6
Peptide accession
A0A4X1TRS6
Residue number A
36
Residue number B
39
Peptide name
RNA polymerase II subunit K
Ligandability
Cysteine 36 of RNA polymerase II subunit K
Cysteine 39 of RNA polymerase II subunit K
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