a tool for identifying drug-targetable redox-active disulphides

IGL c4029_light_IGKV1-39_IGKJ2

Intramolecular

Cysteine 23 and cysteine 88

A redox-regulated disulphide may form within IGL c4029_light_IGKV1-39_IGKJ2 between cysteines 23 and 88.

Details

Redox score ?

79

PDB code

Structure name

sars-cov-2 spike protein in complex with three human neutralizing antibodies

Structure deposition date

2022-01-01

Thiol separation (Å)

2

Half-sphere exposure sum ?

85

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

23

Residue number B

88

Peptide name

IGL c4029_light_IGKV1-39_IGKJ2

Ligandability

Cysteine 23 of IGL c4029_light_IGKV1-39_IGKJ2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 88 of IGL c4029_light_IGKV1-39_IGKJ2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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