ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

IGH + IGL c137_light_IGLV2-8_IGLJ2

Intramolecular
Cysteine 22 and cysteine 90
A redox-regulated disulphide may form within IGH + IGL c137_light_IGLV2-8_IGLJ2 between cysteines 22 and 90 (23 and 88 respectively in this structure).

Details

Redox score ?
79
PDB code
6xey
Structure name
cryo-em structure of the sars-cov-2 spike glycoprotein bound to fab 2- 4
Structure deposition date
2020-06-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
92
Minimum pKa ?
nan
% buried
nan
Peptide accession
A0A5C2GJG2
Residue number A
22
Residue number B
90
Peptide name
IGH + IGL c137_light_IGLV2-8_IGLJ2

Ligandability

Cysteine 22 of IGH + IGL c137_light_IGLV2-8_IGLJ2

Cysteine 90 of IGH + IGL c137_light_IGLV2-8_IGLJ2

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