ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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IG c335_light_IGLV1-40_IGLJ3

Intramolecular
Cysteine 22 and cysteine 90
A redox-regulated disulphide may form within IG c335_light_IGLV1-40_IGLJ3 between cysteines 22 and 90.

Details

Redox score ?
73
PDB code
7wp2
Structure name
cryo-em structure of sars-cov-2 c
Structure deposition date
2022-01-22
Thiol separation (Å)
4
Half-sphere exposure sum ?
90
Minimum pKa ?
8
% buried
83
Peptide accession
A0A5C2GQT9
Residue number A
22
Residue number B
90
Peptide name
IG c335_light_IGLV1-40_IGLJ3

Ligandability

Cysteine 22 of IG c335_light_IGLV1-40_IGLJ3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 90 of IG c335_light_IGLV1-40_IGLJ3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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