a tool for identifying drug-targetable redox-active disulphides

Ig lamda chain variable region

Intramolecular

Cysteine 24 and cysteine 91

A redox-regulated disulphide may form within Ig lamda chain variable region between cysteines 24 and 91.

Details

Redox score ?

79

PDB code

Structure name

foot and mouth disease virus o/tibet/99-bound the single chain fragmen antibody c4

Structure deposition date

2021-04-21

Thiol separation (Å)

2

Half-sphere exposure sum ?

98

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

24

Residue number B

91

Peptide name

Ig lamda chain variable region

Ligandability

Cysteine 24 of Ig lamda chain variable region

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 91 of Ig lamda chain variable region

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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