ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

mitochondrial sodium/hydrogen exchanger 9B2

Intramolecular
Cysteine 211 and cysteine 216
A redox-regulated disulphide may form within mitochondrial sodium/hydrogen exchanger 9B2 between cysteines 211 and 216. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
7p1k
Structure name
cryo em structure of bison nha2 in nano disc structure
Structure deposition date
2021-07-01
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
58
Peptide accession
A0A6P3HVI0
Residue number A
211
Residue number B
216
Peptide name
mitochondrial sodium/hydrogen exchanger 9B2

Ligandability

Cysteine 211 of mitochondrial sodium/hydrogen exchanger 9B2

Cysteine 216 of mitochondrial sodium/hydrogen exchanger 9B2

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