ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Intermolecular
Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 137
A redox-regulated disulphide may form between cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 137 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (154 and 112 respectively in this structure).

Details

Redox score ?
72
PDB code
7zeb
Structure name
complex i from ovis aries at ph9, closed state
Structure deposition date
2022-03-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
75
Minimum pKa ?
8
% buried
100
Peptide A name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Peptide B name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Peptide A accession
A0A6P3EI17
Peptide B accession
A0A836CQA7
Peptide A residue number
155
Peptide B residue number
137

Ligandability

Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 137 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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