ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Intermolecular
Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 141
A redox-regulated disulphide may form between cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 and cysteine 141 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial.

Details

Redox score ?
70
PDB code
7vy9
Structure name
membrane arm of active state ci from q10-nadh dataset
Structure deposition date
2021-11-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
7
% buried
100
Peptide A name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Peptide B name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Peptide A accession
A0A4X1VYV0
Peptide B accession
A0A8D1EYI7
Peptide A residue number
155
Peptide B residue number
141

Ligandability

Cysteine 155 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

Cysteine 141 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

If this tool was useful for finding a disulphide, please cite: