cAMP-dependent protein kinase

Intermolecular

Cysteine 200 and cysteine 114 of cAMP-dependent protein kinase type II-beta regulatory subunit

A redox-regulated disulphide may form between cysteine 200 of cAMP-dependent protein kinase and cysteine 114 of cAMP-dependent protein kinase type II-beta regulatory subunit (199 and 114 respectively in this structure).

Details

Redox score ?

PDB code

3tnq

Structure name

structure and allostery of the pka riib tetrameric holoenzyme

Structure deposition date

2011-09-01

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide A name

cAMP-dependent protein kinase

Peptide B name

cAMP-dependent protein kinase type II-beta regulatory subunit

Peptide A accession

A1L1M0

Peptide B accession

P31324

Peptide A residue number

200

Peptide B residue number

114

Ligandability

Cysteine 200 of cAMP-dependent protein kinase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.