a tool for identifying drug-targetable redox-active disulphides

Major urinary protein 10

Intramolecular

Cysteine 82 and cysteine 175

A redox-regulated disulphide may form within Major urinary protein 10 between cysteines 82 and 175 (64 and 157 respectively in this structure).

Details

Redox score ?

92

PDB code

Structure name

crystal structure of apo-mup

Structure deposition date

2007-02-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

nan

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

82

Residue number B

175

Peptide name

Major urinary protein 10

Ligandability

Cysteine 82 of Major urinary protein 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 175 of Major urinary protein 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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