ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Carboxypeptidase A1

Intramolecular
Cysteine 248 and cysteine 271
A redox-regulated disulphide may form within Carboxypeptidase A1 between cysteines 248 and 271 (138 and 161 respectively in this structure).

Details

Redox score ?
84
PDB code
3hlp
Structure name
carboxypeptidase a liganded to an organic small-molecule: conformational changes
Structure deposition date
2009-05-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
A6H6Y4
Residue number A
248
Residue number B
271
Peptide name
Carboxypeptidase A1

Ligandability

Cysteine 248 of Carboxypeptidase A1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 271 of Carboxypeptidase A1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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