a tool for identifying drug-targetable redox-active disulphides

Glycerol-3-phosphate phosphatase

Intramolecular

Cysteine 104 and cysteine 243

A redox-regulated disulphide may form within Glycerol-3-phosphate phosphatase between cysteines 104 and 243.

Details

Redox score ?

66

PDB code

Structure name

phosphoglycolate phosphatase from mus musculus

Structure deposition date

2021-09-08

Thiol separation (Å)

4

Half-sphere exposure sum ?

86

Minimum pK_a ?

nan

% buried

50

Peptide accession

Residue number A

104

Residue number B

243

Peptide name

Glycerol-3-phosphate phosphatase

Ligandability

Cysteine 104 of Glycerol-3-phosphate phosphatase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 243 of Glycerol-3-phosphate phosphatase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: