ERI1 exoribonuclease 2

A redox-regulated disulphide may form within ERI1 exoribonuclease 2 between cysteines 113 and 118. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7n8w

Structure name

crystal structure of eri2 nuclease bound to ramp

Structure deposition date

2021-06-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

A8K979

Residue number A

113

Residue number B

118

Peptide name

ERI1 exoribonuclease 2

Ligandability

Cysteine 113 of ERI1 exoribonuclease 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 118 of ERI1 exoribonuclease 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within ERI1 exoribonuclease 2 between cysteines 160 and 165. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7n8w

Structure name

crystal structure of eri2 nuclease bound to ramp

Structure deposition date

2021-06-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

A8K979

Residue number A

160

Residue number B

165

Peptide name

ERI1 exoribonuclease 2

Ligandability

Cysteine 160 of ERI1 exoribonuclease 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 165 of ERI1 exoribonuclease 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within ERI1 exoribonuclease 2 between cysteines 113 and 165. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?