Guanine nucleotide-binding protein G(t) subunit alpha-3

Intermolecular

Cysteine 140 of Rhodopsin and cysteine 351

A redox-regulated disulphide may form between cysteine 140 of Rhodopsin and cysteine 351 of Guanine nucleotide-binding protein G(t) subunit alpha-3 (140 and 347 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4a4m

Structure name

crystal structure of the light-activated constitutively active n2c, m257y,d282c rhodopsin mutant in complex with a peptide resembling the c-terminus of the galpha-protein subunit (gact)

Structure deposition date

2011-10-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Rhodopsin

Peptide B name

Guanine nucleotide-binding protein G(t) subunit alpha-3

Peptide A accession

P02699