Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Intramolecular
Cysteine 216 and cysteine 218
Cysteine 384 and cysteine 403
Cysteine 373 and cysteine 384
Cysteine 403 and cysteine 404
Cysteine 373 and cysteine 403
Cysteine 384 and cysteine 404
6e31 A 216 A 218
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 216 and 218.
Details
Redox score ?
77
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
5
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
11
Peptide accession
B1AYC9
Residue number A
216
Residue number B
218
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 216 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 218 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
6e31 A 384 A 403
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 384 and 403.
Details
Redox score ?
74
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
7
% buried
62
Peptide accession
B1AYC9
Residue number A
384
Residue number B
403
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 384 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 403 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
6e31 A 373 A 384
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 373 and 384.
Details
Redox score ?
74
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
4
Half-sphere exposure sum ?
72
Minimum pKa ?
8
% buried
72
Peptide accession
B1AYC9
Residue number A
373
Residue number B
384
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 373 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 384 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
6e31 A 403 A 404
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 403 and 404. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
7
Half-sphere exposure sum ?
81
Minimum pKa ?
7
% buried
66
Peptide accession
B1AYC9
Residue number A
403
Residue number B
404
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 403 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 404 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
6e31 A 373 A 403
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 373 and 403. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
8
Half-sphere exposure sum ?
74
Minimum pKa ?
7
% buried
62
Peptide accession
B1AYC9
Residue number A
373
Residue number B
403
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 373 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 403 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
6e31 A 384 A 404
A redox-regulated disulphide may form within Amyloid beta (A4) protein-binding, family B, member 1 interacting protein between cysteines 384 and 404. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
6e31
Structure name
crystal structure of riam in an autoinhibited configuration
Structure deposition date
2018-07-12
Thiol separation (Å)
7
Half-sphere exposure sum ?
79
Minimum pKa ?
13
% buried
76
Peptide accession
B1AYC9
Residue number A
384
Residue number B
404
Peptide name
Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Ligandability
Cysteine 384 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
Cysteine 404 of Amyloid beta (A4) protein-binding, family B, member 1 interacting protein
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