a tool for identifying drug-targetable redox-active disulphides

Transient receptor potential cation channel subfamily V member 3

Intramolecular

Cysteine 612 and cysteine 619

A redox-regulated disulphide may form within Transient receptor potential cation channel subfamily V member 3 between cysteines 612 and 619.

Details

Redox score ?

91

PDB code

Structure name

structure of human trpv3 in complex with trpvicin

Structure deposition date

2022-04-14

Thiol separation (Å)

3

Half-sphere exposure sum ?

35

Minimum pK_a ?

8

% buried

0

Peptide accession

Residue number A

612

Residue number B

619

Peptide name

Transient receptor potential cation channel subfamily V member 3

Ligandability

Cysteine 612 of Transient receptor potential cation channel subfamily V member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 619 of Transient receptor potential cation channel subfamily V member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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