a tool for identifying drug-targetable redox-active disulphides

Endogenous retrovirus group S71 member 1 Env polyprotein

Intramolecular

Cysteine 549 and cysteine 556

A redox-regulated disulphide may form within Endogenous retrovirus group S71 member 1 Env polyprotein between cysteines 549 and 556.

Details

Redox score ?

83

PDB code

Structure name

structure of the core postfusion porcine endogenous retrovirus fusion protein

Structure deposition date

2021-09-20

Thiol separation (Å)

2

Half-sphere exposure sum ?

52

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

549

Residue number B

556

Peptide name

Endogenous retrovirus group S71 member 1 Env polyprotein

Ligandability

Cysteine 549 of Endogenous retrovirus group S71 member 1 Env polyprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 556 of Endogenous retrovirus group S71 member 1 Env polyprotein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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