ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

cDNA FLJ56608, highly similar to Homo sapiens chloride channel, calcium activated, family member 1 (CLCA1), mRNA

Intramolecular
Cysteine 149 and cysteine 184
A redox-regulated disulphide may form within cDNA FLJ56608, highly similar to Homo sapiens chloride channel, calcium activated, family member 1 (CLCA1), mRNA between cysteines 149 and 184 (386 and 421 respectively in this structure).

Details

Redox score ?
82
PDB code
6pyx
Structure name
calcium activated chloride channel regulator 1 (clca1) vwa domain
Structure deposition date
2019-07-31
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
B4DUZ6
Residue number A
149
Residue number B
184
Peptide name
cDNA FLJ56608, highly similar to Homo sapiens chloride channel, calcium activated, family member 1 (CLCA1), mRNA

Ligandability

Cysteine 149 of cDNA FLJ56608, highly similar to Homo sapiens chloride channel, calcium activated, family member 1 (CLCA1), mRNA

Cysteine 184 of cDNA FLJ56608, highly similar to Homo sapiens chloride channel, calcium activated, family member 1 (CLCA1), mRNA

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