ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Intramolecular
Cysteine 161 and cysteine 224
Cysteine 263 and cysteine 319
A redox-regulated disulphide may form within cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain between cysteines 161 and 224 (101 and 164 respectively in this structure).

Details

Redox score ?
81
PDB code
5vge
Structure name
crystal structure of hla-c*07:02 in complex with ryr peptide
Structure deposition date
2017-04-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
80
Minimum pKa ?
nan
% buried
nan
Peptide accession
B4DVY0
Residue number A
161
Residue number B
224
Peptide name
cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Ligandability

Cysteine 161 of cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 224 of cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain between cysteines 263 and 319 (203 and 259 respectively in this structure).

Details

Redox score ?
80
PDB code
5vge
Structure name
crystal structure of hla-c*07:02 in complex with ryr peptide
Structure deposition date
2017-04-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
82
Minimum pKa ?
nan
% buried
nan
Peptide accession
B4DVY0
Residue number A
263
Residue number B
319
Peptide name
cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Ligandability

Cysteine 263 of cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 319 of cDNA FLJ54183, highly similar to HLA class I histocompatibility antigen, Cw-7 alpha chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: