a tool for identifying drug-targetable redox-active disulphides

Beta-2-microglobulin

Intramolecular

Cysteine 52 and cysteine 106

A redox-regulated disulphide may form within Beta-2-microglobulin between cysteines 52 and 106.

Details

Redox score ?

79

PDB code

Structure name

mhc complexed to 11mer peptide

Structure deposition date

2015-11-30

Thiol separation (Å)

2

Half-sphere exposure sum ?

85

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

52

Residue number B

106

Peptide name

Beta-2-microglobulin

Ligandability

Cysteine 52 of Beta-2-microglobulin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 106 of Beta-2-microglobulin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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