ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Phosphoinositide kinase, FYVE-type zinc finger containing

Intramolecular
Cysteine 751 and cysteine 775
A redox-regulated disulphide may form within Phosphoinositide kinase, FYVE-type zinc finger containing between cysteines 751 and 775 (307 and 331 respectively in this structure).

Details

Redox score ?
60
PDB code
7k2v
Structure name
pikfyve/fig4/vac14 complex centered on pikfyve - map2
Structure deposition date
2020-09-09
Thiol separation (Å)
5
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
77
Peptide accession
E9PDH4
Residue number A
751
Residue number B
775
Peptide name
Phosphoinositide kinase, FYVE-type zinc finger containing

Ligandability

Cysteine 751 of Phosphoinositide kinase, FYVE-type zinc finger containing

Cysteine 775 of Phosphoinositide kinase, FYVE-type zinc finger containing

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