5-hydroxytryptamine (serotonin) receptor 3A

Intramolecular

A redox-regulated disulphide may form within 5-hydroxytryptamine (serotonin) receptor 3A between cysteines 162 and 176 (135 and 149 respectively in this structure).

Details

Redox score ?

PDB code

6np0

Structure name

cryo-em structure of 5ht3a receptor in presence of granisetron

Structure deposition date

2019-01-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

E9QLC0

Residue number A

162

Residue number B

176

Peptide name

5-hydroxytryptamine (serotonin) receptor 3A

Ligandability

Cysteine 162 of 5-hydroxytryptamine (serotonin) receptor 3A

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.