ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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26S proteasome non-ATPase regulatory subunit 8

Intramolecular
Cysteine 115 and cysteine 161
A redox-regulated disulphide may form within 26S proteasome non-ATPase regulatory subunit 8 between cysteines 115 and 161.

Details

Redox score ?
75
PDB code
6epf
Structure name
ground state 26s proteasome (gs1)
Structure deposition date
2017-10-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
50
Peptide accession
F1LMQ3
Residue number A
115
Residue number B
161
Peptide name
26S proteasome non-ATPase regulatory subunit 8

Ligandability

Cysteine 115 of 26S proteasome non-ATPase regulatory subunit 8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 161 of 26S proteasome non-ATPase regulatory subunit 8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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