ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

Intramolecular
Cysteine 24 and cysteine 58
A redox-regulated disulphide may form within NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 between cysteines 24 and 58.

Details

Redox score ?
83
PDB code
7v31
Structure name
active state complex i from rotenone dataset
Structure deposition date
2021-08-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
F1RGE3
Residue number A
24
Residue number B
58
Peptide name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

Ligandability

Cysteine 24 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 58 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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