a tool for identifying drug-targetable redox-active disulphides

39S ribosomal protein L38, mitochondrial

Intramolecular

Cysteine 252 and cysteine 290

A redox-regulated disulphide may form within 39S ribosomal protein L38, mitochondrial between cysteines 252 and 290.

Details

Redox score ?

68

PDB code

Structure name

structure of the large subunit of the mammalian mitoribosome, part 2 of 2

Structure deposition date

2014-09-25

Thiol separation (Å)

5

Half-sphere exposure sum ?

54

Minimum pK_a ?

9

% buried

48

Peptide accession

Residue number A

252

Residue number B

290

Peptide name

39S ribosomal protein L38, mitochondrial

Ligandability

Cysteine 252 of 39S ribosomal protein L38, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 290 of 39S ribosomal protein L38, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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