ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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ATP synthase lipid-binding protein

Intermolecular
Cysteine 99 and cysteine 99
A redox-regulated disulphide may form between two units of ATP synthase lipid-binding protein at cysteines 99 and 99 (64 and 64 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
34
PDB code
6zmr
Structure name
porcine atp synthase fo domain
Structure deposition date
2020-07-03
Thiol separation (Å)
9
Half-sphere exposure sum ?
87
Minimum pKa ?
12
% buried
94
Peptide A name
ATP synthase lipid-binding protein
Peptide B name
ATP synthase lipid-binding protein
Peptide A accession
F1RWF6
Peptide B accession
F1RWF6
Peptide A residue number
99
Peptide B residue number
99

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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