ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S2, mitochondrial

Intramolecular
Cysteine 161 and cysteine 249
A redox-regulated disulphide may form within 28S ribosomal protein S2, mitochondrial between cysteines 161 and 249. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
5aj3
Structure name
structure of the small subunit of the mammalian mitoribosome
Structure deposition date
2015-02-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
70
Minimum pKa ?
11
% buried
88
Peptide accession
F1S001
Residue number A
161
Residue number B
249
Peptide name
28S ribosomal protein S2, mitochondrial

Ligandability

Cysteine 161 of 28S ribosomal protein S2, mitochondrial

Cysteine 249 of 28S ribosomal protein S2, mitochondrial

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