ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

39S ribosomal protein L46, mitochondrial

Intramolecular
Cysteine 52 and cysteine 210
A redox-regulated disulphide may form within 39S ribosomal protein L46, mitochondrial between cysteines 52 and 210. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
4v1a
Structure name
structure of the large subunit of the mammalian mitoribosome, part 2 of 2
Structure deposition date
2014-09-25
Thiol separation (Å)
6
Half-sphere exposure sum ?
92
Minimum pKa ?
12
% buried
100
Peptide accession
F1SRT0
Residue number A
52
Residue number B
210
Peptide name
39S ribosomal protein L46, mitochondrial

Ligandability

Cysteine 52 of 39S ribosomal protein L46, mitochondrial

Cysteine 210 of 39S ribosomal protein L46, mitochondrial

If this tool was useful for finding a disulphide, please cite: