ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

28S ribosomal protein S5, mitochondrial isoform X2

Intramolecular
Cysteine 316 and cysteine 324
A redox-regulated disulphide may form within 28S ribosomal protein S5, mitochondrial isoform X2 between cysteines 316 and 324. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
57
PDB code
5aj3
Structure name
structure of the small subunit of the mammalian mitoribosome
Structure deposition date
2015-02-20
Thiol separation (Å)
5
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
100
Peptide accession
F1SU66
Residue number A
316
Residue number B
324
Peptide name
28S ribosomal protein S5, mitochondrial isoform X2

Ligandability

Cysteine 316 of 28S ribosomal protein S5, mitochondrial isoform X2

Cysteine 324 of 28S ribosomal protein S5, mitochondrial isoform X2

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