Cytotoxic T-lymphocyte protein 4
Intramolecular
Cysteine 92 and cysteine 111
Cysteine 65 and cysteine 137
Cysteine 65 and cysteine 111
Cysteine 65 and cysteine 92
Cysteine 92 and cysteine 137
Cysteine 111 and cysteine 137
4n8p A 86 A 105
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 92 and 111 (86 and 105 respectively in this structure).
Details
Redox score ?
86
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
53
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
92
Residue number B
111
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 92 of Cytotoxic T-lymphocyte protein 4
Cysteine 111 of Cytotoxic T-lymphocyte protein 4
4n8p A 59 A 131
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 65 and 137 (59 and 131 respectively in this structure).
Details
Redox score ?
82
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
65
Residue number B
137
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 65 of Cytotoxic T-lymphocyte protein 4
Cysteine 137 of Cytotoxic T-lymphocyte protein 4
4n8p A 59 A 105
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 65 and 111 (59 and 105 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
65
Residue number B
111
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 65 of Cytotoxic T-lymphocyte protein 4
Cysteine 111 of Cytotoxic T-lymphocyte protein 4
4n8p A 59 A 86
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 65 and 92 (59 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
43
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
65
Residue number B
92
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 65 of Cytotoxic T-lymphocyte protein 4
Cysteine 92 of Cytotoxic T-lymphocyte protein 4
4n8p A 86 A 131
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 92 and 137 (86 and 131 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
92
Residue number B
137
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 92 of Cytotoxic T-lymphocyte protein 4
Cysteine 137 of Cytotoxic T-lymphocyte protein 4
4n8p A 105 A 131
A redox-regulated disulphide may form within Cytotoxic T-lymphocyte protein 4 between cysteines 111 and 137 (105 and 131 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
4n8p
Structure name
crystal structure of a strand swapped ctla-4 from duckbill platypus [psi-nysgrc-012711]
Structure deposition date
2013-10-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
64
Minimum pKa ?
nan
% buried
nan
Peptide accession
F6ZMI5
Residue number A
111
Residue number B
137
Peptide name
Cytotoxic T-lymphocyte protein 4
Ligandability
Cysteine 111 of Cytotoxic T-lymphocyte protein 4
Cysteine 137 of Cytotoxic T-lymphocyte protein 4
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