Anti-human Langerin 2G3 lambda chain

Intermolecular

Cysteine 13 of Isoform 2 of Immunoglobulin heavy constant mu and cysteine 233

Intramolecular

A redox-regulated disulphide may form between cysteine 13 of Isoform 2 of Immunoglobulin heavy constant mu and cysteine 233 of Anti-human Langerin 2G3 lambda chain (153 and 233 respectively in this structure).

Details

Redox score ?

PDB code

8ema

Structure name

mouse full length b cell receptor

Structure deposition date

2022-09-27

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide A name

Isoform 2 of Immunoglobulin heavy constant mu

Peptide B name

Anti-human Langerin 2G3 lambda chain

Peptide A accession

P01872-2

Peptide B accession

G0YP42

Peptide A residue number

Peptide B residue number

233

Ligandability

Cysteine 13 of Isoform 2 of Immunoglobulin heavy constant mu

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 233 of Anti-human Langerin 2G3 lambda chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Anti-human Langerin 2G3 lambda chain between cysteines 41 and 109.

Details

Redox score ?

PDB code

8ema

Structure name

mouse full length b cell receptor

Structure deposition date

2022-09-27

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

G0YP42

Residue number A

Residue number B

109

Peptide name

Anti-human Langerin 2G3 lambda chain

Ligandability

Cysteine 41 of Anti-human Langerin 2G3 lambda chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 109 of Anti-human Langerin 2G3 lambda chain

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Anti-human Langerin 2G3 lambda chain between cysteines 156 and 215 (637 and 696 respectively in this structure).