a tool for identifying drug-targetable redox-active disulphides

Allergen Fel d 4

Intramolecular

Cysteine 136 and cysteine 229

A redox-regulated disulphide may form within Allergen Fel d 4 between cysteines 136 and 229 (66 and 159 respectively in this structure).

Details

Redox score ?

86

PDB code

Structure name

structure of odorant binding protein 3 from giant panda (ailuropoda melanoleuca)

Structure deposition date

2017-03-17

Thiol separation (Å)

2

Half-sphere exposure sum ?

50

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

136

Residue number B

229

Peptide name

Allergen Fel d 4

Ligandability

Cysteine 136 of Allergen Fel d 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 229 of Allergen Fel d 4

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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