ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

40S ribosomal protein S3a

Intramolecular
Cysteine 139 and cysteine 201
A redox-regulated disulphide may form within 40S ribosomal protein S3a between cysteines 139 and 201. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
7jqb
Structure name
sars-cov-2 nsp1 and rabbit 40s ribosome complex
Structure deposition date
2020-08-10
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
12
% buried
91
Peptide accession
G1SS70
Residue number A
139
Residue number B
201
Peptide name
40S ribosomal protein S3a

Ligandability

Cysteine 139 of 40S ribosomal protein S3a

Cysteine 201 of 40S ribosomal protein S3a

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