ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Signal recognition particle receptor subunit beta

Intramolecular
Cysteine 179 and cysteine 246
A redox-regulated disulphide may form within Signal recognition particle receptor subunit beta between cysteines 179 and 246. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
52
PDB code
7obq
Structure name
srp-sr at the distal site conformation
Structure deposition date
2021-04-23
Thiol separation (Å)
6
Half-sphere exposure sum ?
82
Minimum pKa ?
11
% buried
86
Peptide accession
G1STG2
Residue number A
179
Residue number B
246
Peptide name
Signal recognition particle receptor subunit beta

Ligandability

Cysteine 179 of Signal recognition particle receptor subunit beta

Cysteine 246 of Signal recognition particle receptor subunit beta

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