Eukaryotic translation initiation factor 3 subunit K

Intramolecular

A redox-regulated disulphide may form within Eukaryotic translation initiation factor 3 subunit K between cysteines 85 and 87. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

5a5t

Structure name

structure of mammalian eif3 in the context of the 43s preinitiation complex

Structure deposition date

2015-06-21

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

G1T3L2

Residue number A

Residue number B

Peptide name

Eukaryotic translation initiation factor 3 subunit K

Ligandability

Cysteine 85 of Eukaryotic translation initiation factor 3 subunit K

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.