Nucleotide binding oligomerization domain containing 2
Intramolecular
Cysteine 605 and cysteine 683
Cysteine 679 and cysteine 683
Cysteine 786 and cysteine 790
Cysteine 311 and cysteine 535
Cysteine 806 and cysteine 832
Cysteine 605 and cysteine 679
Cysteine 326 and cysteine 327
Cysteine 790 and cysteine 815
Cysteine 752 and cysteine 786
Cysteine 786 and cysteine 815
Cysteine 534 and cysteine 535
5irm A 612 A 690
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 605 and 683 (612 and 690 respectively in this structure).
Details
Redox score ?
79
PDB code
5irm
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form2)
Structure deposition date
2016-03-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
8
% buried
42
Peptide accession
G1T469
Residue number A
605
Residue number B
683
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 605 of Nucleotide binding oligomerization domain containing 2
Cysteine 683 of Nucleotide binding oligomerization domain containing 2
5irl A 686 A 690
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 679 and 683 (686 and 690 respectively in this structure).
Details
Redox score ?
72
PDB code
5irl
Structure name
crystal structure of rabbit nod2 ser mutant in an adp-bound state
Structure deposition date
2016-03-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
7
% buried
52
Peptide accession
G1T469
Residue number A
679
Residue number B
683
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 679 of Nucleotide binding oligomerization domain containing 2
Cysteine 683 of Nucleotide binding oligomerization domain containing 2
5irm C 793 C 797
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 786 and 790 (793 and 797 respectively in this structure).
Details
Redox score ?
67
PDB code
5irm
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form2)
Structure deposition date
2016-03-14
Thiol separation (Å)
5
Half-sphere exposure sum ?
71
Minimum pKa ?
8
% buried
100
Peptide accession
G1T469
Residue number A
786
Residue number B
790
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 786 of Nucleotide binding oligomerization domain containing 2
Cysteine 790 of Nucleotide binding oligomerization domain containing 2
5irn A 318 A 542
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 311 and 535 (318 and 542 respectively in this structure).
Details
Redox score ?
62
PDB code
5irn
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form1)
Structure deposition date
2016-03-14
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
54
Peptide accession
G1T469
Residue number A
311
Residue number B
535
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 311 of Nucleotide binding oligomerization domain containing 2
Cysteine 535 of Nucleotide binding oligomerization domain containing 2
5irl A 813 A 839
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 806 and 832 (813 and 839 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
5irl
Structure name
crystal structure of rabbit nod2 ser mutant in an adp-bound state
Structure deposition date
2016-03-14
Thiol separation (Å)
6
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
58
Peptide accession
G1T469
Residue number A
806
Residue number B
832
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 806 of Nucleotide binding oligomerization domain containing 2
Cysteine 832 of Nucleotide binding oligomerization domain containing 2
5irl A 612 A 686
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 605 and 679 (612 and 686 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
5irl
Structure name
crystal structure of rabbit nod2 ser mutant in an adp-bound state
Structure deposition date
2016-03-14
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
7
% buried
37
Peptide accession
G1T469
Residue number A
605
Residue number B
679
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 605 of Nucleotide binding oligomerization domain containing 2
Cysteine 679 of Nucleotide binding oligomerization domain containing 2
5irn A 333 A 334
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 326 and 327 (333 and 334 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
5irn
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form1)
Structure deposition date
2016-03-14
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
11
% buried
75
Peptide accession
G1T469
Residue number A
326
Residue number B
327
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 326 of Nucleotide binding oligomerization domain containing 2
Cysteine 327 of Nucleotide binding oligomerization domain containing 2
5irn A 797 A 822
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 790 and 815 (797 and 822 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5irn
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form1)
Structure deposition date
2016-03-14
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
72
Peptide accession
G1T469
Residue number A
790
Residue number B
815
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 790 of Nucleotide binding oligomerization domain containing 2
Cysteine 815 of Nucleotide binding oligomerization domain containing 2
5irn A 759 A 793
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 752 and 786 (759 and 793 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5irn
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form1)
Structure deposition date
2016-03-14
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
8
% buried
100
Peptide accession
G1T469
Residue number A
752
Residue number B
786
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 752 of Nucleotide binding oligomerization domain containing 2
Cysteine 786 of Nucleotide binding oligomerization domain containing 2
5irm C 793 C 822
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 786 and 815 (793 and 822 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
5irm
Structure name
crystal structure of rabbit nod2 in an adp-bound state (crystal form2)
Structure deposition date
2016-03-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
8
% buried
75
Peptide accession
G1T469
Residue number A
786
Residue number B
815
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 786 of Nucleotide binding oligomerization domain containing 2
Cysteine 815 of Nucleotide binding oligomerization domain containing 2
5irl A 541 A 542
A redox-regulated disulphide may form within Nucleotide binding oligomerization domain containing 2 between cysteines 534 and 535 (541 and 542 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
5irl
Structure name
crystal structure of rabbit nod2 ser mutant in an adp-bound state
Structure deposition date
2016-03-14
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
62
Peptide accession
G1T469
Residue number A
534
Residue number B
535
Peptide name
Nucleotide binding oligomerization domain containing 2
Ligandability
Cysteine 534 of Nucleotide binding oligomerization domain containing 2
Cysteine 535 of Nucleotide binding oligomerization domain containing 2
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