a tool for identifying drug-targetable redox-active disulphides

TNF superfamily member 18

Intramolecular

Cysteine 98 and cysteine 118

A redox-regulated disulphide may form within TNF superfamily member 18 between cysteines 98 and 118 (6 and 26 respectively in this structure).

Details

Redox score ?

85

PDB code

Structure name

crystal structure of rabbit gitrl

Structure deposition date

2012-01-13

Thiol separation (Å)

2

Half-sphere exposure sum ?

63

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

98

Residue number B

118

Peptide name

TNF superfamily member 18

Ligandability

Cysteine 98 of TNF superfamily member 18

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 118 of TNF superfamily member 18

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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