40S ribosomal protein S27
Intramolecular
Cysteine 40 and cysteine 59
Cysteine 56 and cysteine 59
Cysteine 40 and cysteine 56
Cysteine 37 and cysteine 56
Cysteine 37 and cysteine 59
Cysteine 37 and cysteine 40
Cysteine 37 and cysteine 77
Cysteine 64 and cysteine 77
Cysteine 56 and cysteine 77
Cysteine 59 and cysteine 64
More...Cysteine 40 and cysteine 77
Cysteine 59 and cysteine 77
Cysteine 56 and cysteine 64
Cysteine 37 and cysteine 64
4kzz b 40 b 59
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 40 and 59.
Details
Redox score ?
84
PDB code
4kzz
Structure name
rabbit 40s ribosomal subunit in complex with mrna, initiator trna and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
32
Minimum pKa ?
9
% buried
0
Peptide accession
G1TZ76
Residue number A
40
Residue number B
59
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 40 of 40S ribosomal protein S27
Cysteine 59 of 40S ribosomal protein S27
4kzx b 56 b 59
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 56 and 59.
Details
Redox score ?
82
PDB code
4kzx
Structure name
rabbit 40s ribosomal subunit in complex with eif1
Structure deposition date
2013-05-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
8
% buried
0
Peptide accession
G1TZ76
Residue number A
56
Residue number B
59
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 56 of 40S ribosomal protein S27
Cysteine 59 of 40S ribosomal protein S27
4kzy b 40 b 56
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 40 and 56.
Details
Redox score ?
82
PDB code
4kzy
Structure name
rabbit 40s ribosomal subunit in complex with eif1 and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
8
% buried
0
Peptide accession
G1TZ76
Residue number A
40
Residue number B
56
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 40 of 40S ribosomal protein S27
Cysteine 56 of 40S ribosomal protein S27
4kzy b 37 b 56
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 37 and 56.
Details
Redox score ?
80
PDB code
4kzy
Structure name
rabbit 40s ribosomal subunit in complex with eif1 and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
0
Peptide accession
G1TZ76
Residue number A
37
Residue number B
56
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 37 of 40S ribosomal protein S27
Cysteine 56 of 40S ribosomal protein S27
4kzz b 37 b 59
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 37 and 59.
Details
Redox score ?
78
PDB code
4kzz
Structure name
rabbit 40s ribosomal subunit in complex with mrna, initiator trna and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
9
% buried
0
Peptide accession
G1TZ76
Residue number A
37
Residue number B
59
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 37 of 40S ribosomal protein S27
Cysteine 59 of 40S ribosomal protein S27
4kzx b 37 b 40
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 37 and 40.
Details
Redox score ?
74
PDB code
4kzx
Structure name
rabbit 40s ribosomal subunit in complex with eif1
Structure deposition date
2013-05-30
Thiol separation (Å)
5
Half-sphere exposure sum ?
43
Minimum pKa ?
10
% buried
0
Peptide accession
G1TZ76
Residue number A
37
Residue number B
40
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 37 of 40S ribosomal protein S27
Cysteine 40 of 40S ribosomal protein S27
4kzx b 37 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 37 and 77.
Details
Redox score ?
67
PDB code
4kzx
Structure name
rabbit 40s ribosomal subunit in complex with eif1
Structure deposition date
2013-05-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
8
Peptide accession
G1TZ76
Residue number A
37
Residue number B
77
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 37 of 40S ribosomal protein S27
Cysteine 77 of 40S ribosomal protein S27
4kzy b 64 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 64 and 77.
Details
Redox score ?
63
PDB code
4kzy
Structure name
rabbit 40s ribosomal subunit in complex with eif1 and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
36
Peptide accession
G1TZ76
Residue number A
64
Residue number B
77
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 64 of 40S ribosomal protein S27
Cysteine 77 of 40S ribosomal protein S27
4kzz b 56 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 56 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
4kzz
Structure name
rabbit 40s ribosomal subunit in complex with mrna, initiator trna and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
51
Minimum pKa ?
8
% buried
8
Peptide accession
G1TZ76
Residue number A
56
Residue number B
77
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 56 of 40S ribosomal protein S27
Cysteine 77 of 40S ribosomal protein S27
5k0y Y 59 Y 64
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 59 and 64. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
5k0y
Structure name
m48s late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eif2 ternary complex and eif3 i and g subunits relocated to the intersubunit face
Structure deposition date
2016-05-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
56
Minimum pKa ?
10
% buried
36
Peptide accession
G1TZ76
Residue number A
59
Residue number B
64
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 59 of 40S ribosomal protein S27
Cysteine 64 of 40S ribosomal protein S27
7syw c 40 c 77
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 40 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
7syw
Structure name
structure of the wt ires eif5b-containing 48s initiation complex, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
10
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
22
Peptide accession
G1TZ76
Residue number A
40
Residue number B
77
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 40 of 40S ribosomal protein S27
Cysteine 77 of 40S ribosomal protein S27
4kzy b 59 b 77
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 59 and 77. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4kzy
Structure name
rabbit 40s ribosomal subunit in complex with eif1 and eif1a
Structure deposition date
2013-05-30
Thiol separation (Å)
10
Half-sphere exposure sum ?
39
Minimum pKa ?
9
% buried
8
Peptide accession
G1TZ76
Residue number A
59
Residue number B
77
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 59 of 40S ribosomal protein S27
Cysteine 77 of 40S ribosomal protein S27
7syi c 56 c 64
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 56 and 64. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
7syi
Structure name
structure of the hcv ires binding to the 40s ribosomal subunit, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
46
Peptide accession
G1TZ76
Residue number A
56
Residue number B
64
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 56 of 40S ribosomal protein S27
Cysteine 64 of 40S ribosomal protein S27
7syx c 37 c 64
A redox-regulated disulphide may form within 40S ribosomal protein S27 between cysteines 37 and 64. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
7syx
Structure name
structure of the delta dii ires eif5b-containing 48s initiation complex, closed conformation
Structure deposition date
2021-11-25
Thiol separation (Å)
10
Half-sphere exposure sum ?
55
Minimum pKa ?
11
% buried
47
Peptide accession
G1TZ76
Residue number A
37
Residue number B
64
Peptide name
40S ribosomal protein S27
Ligandability
Cysteine 37 of 40S ribosomal protein S27
Cysteine 64 of 40S ribosomal protein S27
If this tool was useful for finding a disulphide, please cite: