ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Proteasome 26S subunit, ATPase 6

Intramolecular
Cysteine 207 and cysteine 242
A redox-regulated disulphide may form within Proteasome 26S subunit, ATPase 6 between cysteines 207 and 242. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
6epf
Structure name
ground state 26s proteasome (gs1)
Structure deposition date
2017-10-11
Thiol separation (Å)
8
Half-sphere exposure sum ?
65
Minimum pKa ?
11
% buried
64
Peptide accession
G3V6W6
Residue number A
207
Residue number B
242
Peptide name
Proteasome 26S subunit, ATPase 6

Ligandability

Cysteine 207 of Proteasome 26S subunit, ATPase 6

Cysteine 242 of Proteasome 26S subunit, ATPase 6

If this tool was useful for finding a disulphide, please cite: