SP100 nuclear antigen
Intramolecular
Cysteine 79 and cysteine 82
Cysteine 91 and cysteine 119
Cysteine 79 and cysteine 102
Cysteine 91 and cysteine 94
Cysteine 91 and cysteine 116
Cysteine 94 and cysteine 119
Cysteine 94 and cysteine 116
Cysteine 116 and cysteine 119
Cysteine 82 and cysteine 102
Cysteine 79 and cysteine 162
More...Cysteine 90 and cysteine 91
Cysteine 90 and cysteine 94
Cysteine 82 and cysteine 162
Cysteine 102 and cysteine 162
4ptb A 705 A 708
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 79 and 82 (705 and 708 respectively in this structure).
Details
Redox score ?
89
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
3
% buried
38
Peptide accession
H0Y4R8
Residue number A
79
Residue number B
82
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 79 of SP100 nuclear antigen
Cysteine 82 of SP100 nuclear antigen
4ptb A 717 A 745
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 91 and 119 (717 and 745 respectively in this structure).
Details
Redox score ?
88
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
5
% buried
23
Peptide accession
H0Y4R8
Residue number A
91
Residue number B
119
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 91 of SP100 nuclear antigen
Cysteine 119 of SP100 nuclear antigen
4ptb A 705 A 728
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 79 and 102 (705 and 728 respectively in this structure).
Details
Redox score ?
88
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
3
% buried
48
Peptide accession
H0Y4R8
Residue number A
79
Residue number B
102
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 79 of SP100 nuclear antigen
Cysteine 102 of SP100 nuclear antigen
4ptb B 717 B 720
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 91 and 94 (717 and 720 respectively in this structure).
Details
Redox score ?
86
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
5
% buried
25
Peptide accession
H0Y4R8
Residue number A
91
Residue number B
94
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 91 of SP100 nuclear antigen
Cysteine 94 of SP100 nuclear antigen
4ptb B 717 B 742
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 91 and 116 (717 and 742 respectively in this structure).
Details
Redox score ?
84
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
69
Minimum pKa ?
5
% buried
43
Peptide accession
H0Y4R8
Residue number A
91
Residue number B
116
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 91 of SP100 nuclear antigen
Cysteine 116 of SP100 nuclear antigen
4ptb B 720 B 745
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 94 and 119 (720 and 745 respectively in this structure).
Details
Redox score ?
82
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
8
% buried
22
Peptide accession
H0Y4R8
Residue number A
94
Residue number B
119
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 94 of SP100 nuclear antigen
Cysteine 119 of SP100 nuclear antigen
4ptb B 720 B 742
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 94 and 116 (720 and 742 respectively in this structure).
Details
Redox score ?
79
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
8
% buried
41
Peptide accession
H0Y4R8
Residue number A
94
Residue number B
116
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 94 of SP100 nuclear antigen
Cysteine 116 of SP100 nuclear antigen
4ptb B 742 B 745
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 116 and 119 (742 and 745 respectively in this structure).
Details
Redox score ?
73
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
40
Peptide accession
H0Y4R8
Residue number A
116
Residue number B
119
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 116 of SP100 nuclear antigen
Cysteine 119 of SP100 nuclear antigen
4ptb B 708 B 728
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 82 and 102 (708 and 728 respectively in this structure).
Details
Redox score ?
73
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
33
Peptide accession
H0Y4R8
Residue number A
82
Residue number B
102
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 82 of SP100 nuclear antigen
Cysteine 102 of SP100 nuclear antigen
4ptb B 705 B 788
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 79 and 162 (705 and 788 respectively in this structure).
Details
Redox score ?
65
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
8
Half-sphere exposure sum ?
54
Minimum pKa ?
3
% buried
59
Peptide accession
H0Y4R8
Residue number A
79
Residue number B
162
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 79 of SP100 nuclear antigen
Cysteine 162 of SP100 nuclear antigen
4ptb B 716 B 717
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 90 and 91 (716 and 717 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
62
Minimum pKa ?
5
% buried
18
Peptide accession
H0Y4R8
Residue number A
90
Residue number B
91
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 90 of SP100 nuclear antigen
Cysteine 91 of SP100 nuclear antigen
4ptb A 716 A 720
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 90 and 94 (716 and 720 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
18
Peptide accession
H0Y4R8
Residue number A
90
Residue number B
94
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 90 of SP100 nuclear antigen
Cysteine 94 of SP100 nuclear antigen
4ptb A 708 A 788
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 82 and 162 (708 and 788 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
54
Minimum pKa ?
9
% buried
53
Peptide accession
H0Y4R8
Residue number A
82
Residue number B
162
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 82 of SP100 nuclear antigen
Cysteine 162 of SP100 nuclear antigen
4ptb B 728 B 788
A redox-regulated disulphide may form within SP100 nuclear antigen between cysteines 102 and 162 (728 and 788 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
4ptb
Structure name
crystal structure of human sp100 phd-bromodomain in the free state
Structure deposition date
2014-03-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
11
% buried
60
Peptide accession
H0Y4R8
Residue number A
102
Residue number B
162
Peptide name
SP100 nuclear antigen
Ligandability
Cysteine 102 of SP100 nuclear antigen
Cysteine 162 of SP100 nuclear antigen
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