RNA polymerase II, I and III subunit K
Intramolecular
Cysteine 22 and cysteine 39
Cysteine 22 and cysteine 36
Cysteine 19 and cysteine 36
Cysteine 36 and cysteine 39
Cysteine 19 and cysteine 22
Cysteine 19 and cysteine 39
6ted L 22 L 39
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 22 and 39.
Details
Redox score ?
88
PDB code
6ted
Structure name
structure of complete, activated transcription complex pol ii-dsif- paf-spt6 uncovers allosteric elongation activation by rtf1
Structure deposition date
2019-11-11
Thiol separation (Å)
3
Half-sphere exposure sum ?
66
Minimum pKa ?
3
% buried
66
Peptide accession
I3LN51
Residue number A
22
Residue number B
39
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 22 of RNA polymerase II, I and III subunit K
Cysteine 39 of RNA polymerase II, I and III subunit K
7opd L 22 L 36
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 22 and 36.
Details
Redox score ?
87
PDB code
7opd
Structure name
pol ii-csb-crl4csa-uvssa-spt6-paf (structure 5)
Structure deposition date
2021-05-31
Thiol separation (Å)
3
Half-sphere exposure sum ?
53
Minimum pKa ?
6
% buried
14
Peptide accession
I3LN51
Residue number A
22
Residue number B
36
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 22 of RNA polymerase II, I and III subunit K
Cysteine 36 of RNA polymerase II, I and III subunit K
6exv L 19 L 36
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 19 and 36.
Details
Redox score ?
81
PDB code
6exv
Structure name
structure of mammalian rna polymerase ii elongation complex inhibited by alpha-amanitin
Structure deposition date
2017-11-09
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
7
% buried
25
Peptide accession
I3LN51
Residue number A
19
Residue number B
36
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 19 of RNA polymerase II, I and III subunit K
Cysteine 36 of RNA polymerase II, I and III subunit K
7nvy L 36 L 39
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 36 and 39.
Details
Redox score ?
80
PDB code
7nvy
Structure name
rna polymerase ii pre-initiation complex with closed promoter dna in proximal position
Structure deposition date
2021-03-16
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
7
% buried
16
Peptide accession
I3LN51
Residue number A
36
Residue number B
39
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 36 of RNA polymerase II, I and III subunit K
Cysteine 39 of RNA polymerase II, I and III subunit K
7oo3 L 19 L 22
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 19 and 22.
Details
Redox score ?
78
PDB code
7oo3
Structure name
pol ii-csb-csa-ddb1-uvssa (structure1)
Structure deposition date
2021-05-26
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
8
% buried
28
Peptide accession
I3LN51
Residue number A
19
Residue number B
22
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 19 of RNA polymerase II, I and III subunit K
Cysteine 22 of RNA polymerase II, I and III subunit K
7ozn L 19 L 39
A redox-regulated disulphide may form within RNA polymerase II, I and III subunit K between cysteines 19 and 39.
Details
Redox score ?
77
PDB code
7ozn
Structure name
rna polymerase ii dimer (class 1)
Structure deposition date
2021-06-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
26
Peptide accession
I3LN51
Residue number A
19
Residue number B
39
Peptide name
RNA polymerase II, I and III subunit K
Ligandability
Cysteine 19 of RNA polymerase II, I and III subunit K
Cysteine 39 of RNA polymerase II, I and III subunit K
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