a tool for identifying drug-targetable redox-active disulphides

Beta-2-microglobulin

Intramolecular

Cysteine 208 and cysteine 262

A redox-regulated disulphide may form within Beta-2-microglobulin between cysteines 208 and 262 (25 and 79 respectively in this structure).

Details

Redox score ?

80

PDB code

Structure name

crystal structure of bat (pteropus alecto) mhc class i ptal-n*01:01 in complex with hendra virus-derived peptide hev1

Structure deposition date

2019-01-01

Thiol separation (Å)

2

Half-sphere exposure sum ?

81

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

208

Residue number B

262

Peptide name

Beta-2-microglobulin

Ligandability

Cysteine 208 of Beta-2-microglobulin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 262 of Beta-2-microglobulin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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