Kinesin-like protein KIF2A
Intramolecular
Cysteine 225 and cysteine 525
Cysteine 225 and cysteine 227
Cysteine 309 and cysteine 525
Cysteine 225 and cysteine 309
Cysteine 227 and cysteine 525
Cysteine 227 and cysteine 309
6bbn E 225 E 525
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 225 and 525.
Details
Redox score ?
79
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
3
% buried
86
Peptide accession
O00139
Residue number A
225
Residue number B
525
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 225 of Kinesin-like protein KIF2A
Cysteine 525 of Kinesin-like protein KIF2A
6bbn E 225 E 227
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 225 and 227.
Details
Redox score ?
76
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
3
% buried
84
Peptide accession
O00139
Residue number A
225
Residue number B
227
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 225 of Kinesin-like protein KIF2A
Cysteine 227 of Kinesin-like protein KIF2A
6bbn E 309 E 525
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 309 and 525. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
87
Minimum pKa ?
9
% buried
100
Peptide accession
O00139
Residue number A
309
Residue number B
525
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 309 of Kinesin-like protein KIF2A
Cysteine 525 of Kinesin-like protein KIF2A
6bbn E 225 E 309
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 225 and 309. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
80
Minimum pKa ?
3
% buried
86
Peptide accession
O00139
Residue number A
225
Residue number B
309
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 225 of Kinesin-like protein KIF2A
Cysteine 309 of Kinesin-like protein KIF2A
6bbn E 227 E 525
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 227 and 525. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
84
Minimum pKa ?
17
% buried
97
Peptide accession
O00139
Residue number A
227
Residue number B
525
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 227 of Kinesin-like protein KIF2A
Cysteine 525 of Kinesin-like protein KIF2A
6bbn E 227 E 309
A redox-regulated disulphide may form within Kinesin-like protein KIF2A between cysteines 227 and 309. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
6bbn
Structure name
crystal structure of a curved tubulin complex induced by the kinesin- 13 kif2a
Structure deposition date
2017-10-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
91
Minimum pKa ?
9
% buried
97
Peptide accession
O00139
Residue number A
227
Residue number B
309
Peptide name
Kinesin-like protein KIF2A
Ligandability
Cysteine 227 of Kinesin-like protein KIF2A
Cysteine 309 of Kinesin-like protein KIF2A
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